ReDD-Observatory: Using the Web of Data for Evaluating the Research-Disease Disparity

The ReDD-Observatory is a project to evaluate the disparity between active areas of biomedical research and the global burden of disease using Linked Data and data-driven discovery.


It is widely accepted that there is a large disparity between the availability of treatment options and the prevalence of diseases in the world, thus placing individuals in danger. This disparity is partially caused by the restricted access to information that would allow health- care and research policy makers to formulate more appropriate measures to mitigate this disparity. Specifically, this shortage of information is caused by the difficulty in reliably obtaining and integrating data regarding the disease burden for a given nation and the respective research investments.

In response to these challenges, the Linked Data paradigm provides a simple mechanism for publishing and interlinking structured information on the Web. In conjunction with the ever increasing data on diseases and healthcare research available as Linked Data, an opportunity is created to reduce this information gap that would allow for better policy in response to these disparities.

We present the ReDD-Observatory, an approach for evaluating the Research-Disease Disparity based on the interlinking and integrating of various biomedical data sources.


The figure below provides a birds eye-view of the methodology involved in the ReDD-Observatory.

We first identified relevant datasets to be included that provided relevant information to evaluate the disparity. We not only consider the datasets already present as RDF but also those that are present in unstructured formats. These datasets are:

  1. LinkedCT - the RDF representation of, which is the database of all clinical trials around the world.
  2. Bio2RDF's PubMed - the RDF representation of PubMed, which is a service of the US National Library of Medicine that includes bibliographic information and abstracts of over 19 million publications from MEDLINE and other life science journals.
  3. WHO's Global Health Observatory (GHO), which contains statistical information regarding the mortality and burden of disease classified according to the death and DALY (disability-adjusted life year) estimates grouped by countries and regions. However, since GHO is not available as Linked Data, as the next step we devised a method for representing unstructured data as RDF. We devised a plug-in in OntoWiki to represent statistical data from GHO as RDF. We used the Data Cube Vocabulary for this conversion. More information is present here. In order to ensure the completeness, conciseness and consistency for the selected datasets our next step is to assess the data quality of the datasets. The next challenging step is to interlink the datasets for a number of concepts such as (a) countries, (b) diseases and (c) publications. The assessment of the disparity is then performed with a number of parametrized SPARQL queries. We evaluate the results wrt. information quality and interlinking precision. As a consequence, we are, for the first time, able to provide reliable indicators for the extent of the research-disease disparity around the world in an semi- automated fashion, thus enabling healthcare professionals and policy makers to make more informed decisions.

Further Information

Project Team


by (Editors: ) [BibTex of ]


AKSW at ISWC2017 ( 2017-07-30T05:57:57+02:00 Muhammad Saleem)

2017-07-30T05:57:57+02:00 Muhammad Saleem

We are very pleased to announce that AKSW will be presenting 2 papers at ISWC 2017, which will be held on 21-24 October in Vienna, Austria. The demo and workshops papers have to be announced. Read more about "AKSW at ISWC2017"

AKSW Colloquium, 07.07.2017, Two paper presentations concerning Link Discovery and Knowledge Base Reasoning ( 2017-07-06T21:24:36+02:00 by Daniel Obraczka)

2017-07-06T21:24:36+02:00 by Daniel Obraczka

At the AKSW Colloquium on Friday 7th of July, at 10:40 AM there will be two paper presentations concerning genetic algorithms to learn linkage rules, and differentiable learning of logical rules for knowledge base reasoning. Read more about "AKSW Colloquium, 07.07.2017, Two paper presentations concerning Link Discovery and Knowledge Base Reasoning"

SANSA 0.2 (Semantic Analytics Stack) Released ( 2017-06-13T18:18:28+02:00 by Prof. Dr. Jens Lehmann)

2017-06-13T18:18:28+02:00 by Prof. Dr. Jens Lehmann

The AKSW and Smart Data Analytics groups are happy to announce SANSA 0.2 – the second release of the Scalable Semantic Analytics Stack. Read more about "SANSA 0.2 (Semantic Analytics Stack) Released"

AKSW at ESWC 2017 ( 2017-06-12T10:53:35+02:00 Christopher Schulz)

2017-06-12T10:53:35+02:00 Christopher Schulz

Hello Community! The ESWC 2017 just ended and we give a short report of the course at the conference, especially regarding the AKSW-Group. Our members Dr. Muhammad Saleem, Dr. Mohamed Ahmed Sherif, Claus Stadler, Michael Röder, Prof. Dr. Read more about "AKSW at ESWC 2017"

Four papers accepted at WI 2017 ( 2017-06-10T15:01:31+02:00 Christopher Schulz)

2017-06-10T15:01:31+02:00 Christopher Schulz

Hello Community! We proudly announce that The International Conference on Web Intelligence (WI) accepted four papers by our group. The WI takes place in Leipzig between the 23th – 26th of August. Read more about "Four papers accepted at WI 2017"